Ti-VAMP antibody (158.2)

Vesicle-associated membrane protein 7 (VAMP-7)
Synaptobrevin-like protein 1
Tetanus-insensitive VAMP (Ti-VAMP)
Gene name : VAMP7, SYBL1
As low as $306.10
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00012793
Belongs to the synaptobrevin family. Ti-VAMP is located in late endosomes and in lysosomes and targets the vesicles for fusion with membranes.
More Information
ID Covalab mab0050
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 158.2
Isotype IgG1 / Kappa
Raised in Mouse
Immunogen GST-Ti-VAMP recombinant protein
Activity cross reaction Reacts with human 25 kDa Ti-VAMP protein. Cross reacts with Ti-VAMP from different species (mouse, rat, canine ..)
Species Hu
Labelling None
Form Cell culture supernatant
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Ti-VAMP
Uniprot ID P51809
Gene ID 6845
Applications ELISA, ICC, IF, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/5 to 1/200
- WB : 1/50 to 1/500
Publication - Feldmann A. et al. Transport of the major myelin roteolipid protein is directed by VAMP3 and VAMP7.J Neurosci. 2011 Apr 13;31(15):5659-72.

- Muzerelle A. et al. Tetanus neurotoxin-insensitive vesicle-associated membrane protein localizes to a presynaptic membrane compartment in selected terminal subsets of the rat brain. Neuroscience. 2003;122:59-75.

- Nobumichi Furuta, et al,. Combinational Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Proteins VAMP8 and Vti1b Mediate Fusion of Antimicrobial and Canonical Autophagosomes with Lysosomes. 20 jan 2010.
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