We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
CD8A antibody (OKT8)
CD8a
T-cell surface glycoprotein CD8 alpha chain
T-lymphocyte differentiation antigen T8/Leu-2
Gene : CD8A / MAL
T-cell surface glycoprotein CD8 alpha chain
T-lymphocyte differentiation antigen T8/Leu-2
Gene : CD8A / MAL
As low as
$242.00
In stock
Ref
00124680
The OKT8 monoclonal antibody specifically recognizes the human CD8a molecule, a cell surface receptor of approximately 32-34 kDa. CD8a is expressed either as a heterodimer with the CD8 beta chain (CD8αβ) or as a homodimer (CD8αα). It is found on the majority of thymocytes, as well as on a subset of mature T cells and natural killer (NK) cells. CD8a interacts with MHC class I molecules and, through its association with the protein tyrosine kinase p56lck, plays a crucial role in T-cell development and activation.
| ID Covalab | mab0286-p |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | OKT8 |
| Isotype | IgG2a kappa |
| Raised in | Mouse |
| Immunogen | Human thymocyte membrane glycoproteins |
| Activity cross reaction | Recognizes human CD8a, a surface marker expressed on cytotoxic T lymphocytes and some thymocytes. |
| Species | Human |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | CD8a is a glycoprotein primarily expressed on cytotoxic T cells and plays a crucial role in T-cell activation and immune response. |
| Uniprot ID | P01732 |
| Applications | FC, IF, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user.. The following instructions are only guidelines: |
Write Your Own Review