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Anti-Dityrosine Mouse Antibody
Dityrosine, Dityrosine (DT), DT, DY
As low as
$804.00
In stock
Ref
00123911
ROS such as hydrogen peroxide (H2O2), superoxide, and hydroxyl radicals can react with both the backbone and the side chains of proteins, leading to backbone cleavage and side-chain modifications, respectively. Peroxidases, UV radiation, and hydroxyl radicals catalyze the formation of tyrosyl radicals which then react to form cross-links between proteins (1). This produces dityrosine, a metabolically stable biomarker of protein oxidation (2).
| ID Covalab | mab60834 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 7D4 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Synthetic Dityrosine conjugated to Keyhole Limpet Hemocyanin (KLH). |
| Activity cross reaction | Specific for dityrosine modified proteins. Does not cross-react with 3,5-dibromotyrosine or bromotyrosine modified proteins. |
| Species | Species Independent |
| Form | Purified |
| Preservative | 0.09% Sodium azide |
| Storage instructions | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | Dityrosine |
| Applications | ELISA, ICC/IF, WB |
| Working dilutions | WB (1:1000); ICC/IF (1:50); ELISA (1:1000); optimal dilutions for assays should be determined by the user. |
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