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Anti-6-Nitrotryptophan Mouse Antibody
6-Nitrotryptophan, Nitrotryptophan (NW), Nitrotryptophan, NW, 6-NO2-Trp
As low as
$804.00
In stock
Ref
00123910
6-nitrotryptophan is a major nitrated product of tryptophan residues in proteins reacted with reactive nitrogen species (RNS) (1). Superoxide (O2-) and nitric oxide (NO) react to form peroxynitrous acid, which subsequently nitrates tryptophan residues, modulating protein functions (2). Tryptophan residues are more likely to be nitrated when the indole ring is exposed to the surface of proteins (1).
| ID Covalab | mab60833 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 4F8 |
| Isotype | IgG2b |
| Raised in | Mouse |
| Immunogen | Synthetic 6-Nitrotryptophan modified Keyhole Limpet Hemocyanin (KLH). |
| Activity cross reaction | Specific for 6-Nitrotyrptophan modified proteins. Doss not cross-react with 7-Ketocholoesterol modified proteins. |
| Species | Species Independent |
| Form | Purified |
| Preservative | 0.09% Sodium azide |
| Storage instructions | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | Nitrotryptophan |
| Applications | ELISA, ICC/IF, IHC, WB |
| Working dilutions | WB (1:1000); ICC/IF (1:50); ELISA (1:1000); IHC (1:100); optimal dilutions for assays should be determined by the user. |
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