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Anti-Malondialdehyde Mouse Antibody
Malondialdehyde, MDA, Malondialdehyde (MDA), Malonic aldehyde Propanedial, 1,3-Propanedial, Malonaldehyde
As low as
$804.00
In stock
Ref
00123905
Malondialdehyde (MDA) is the biomarker in greatest diagnostic use, due to its molecular stability. This three-carbon, low-molecular weight aldehyde has a strong affinity for amino acids, which results in adduct formation to both free amino acids and proteins. Increased MDA levels have been found at correlating levels in breast cancer, and lung cancer patients. Other diseased states with elevated MDA levels include diabetes and Alzheimer’s disease. Multiple laboratory techniques exist for quantification of MDA levels, including the thiobarbituric acid reactive substances (TBARS) assay. In addition to use as a biomarker, MDA has been shown to have mutagenic effects on tissues themselves as adduct formation can result in DNA cross-linking.
ID Covalab | mab60828 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | 6H6 |
Isotype | IgG1 |
Raised in | Mouse |
Immunogen | Synthetic Malondialdehyde modified Keyhole Limpet Hemocyanin (KLH). |
Activity cross reaction | Specific for Malondialdehyde conjugated proteins. Does not detect free Malondialdehyde. Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, or Methylglyoxal modified proteins. |
Species | Species Independent |
Form | Purified |
Preservative | 0.09% Sodium azide |
Storage instructions | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
Target | Malondialdehyde |
Applications | ELISA, FACS, FCM, ICC/IF, WB |
Working dilutions | WB (1:1000); ICC/IF (1:50); FACS (1:50); FCM (1:50); ELISA (1:1000); optimal dilutions for assays should be determined by the user. |
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