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CD344 antibody (CH3A4A7)
Frizzled-4Fz-4
hFz4FzE4
CD344
Gene name: FZD4
hFz4FzE4
CD344
Gene name: FZD4
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00122155
CD344 (Frizzled class receptor 4) is a G-protein coupled 7-TM protein, predominantly expressed in fetal neuronal progenitor cells, neuronal intestinal cells, as well as in the kidney, lung, brain, and liver. CD344 is important for regulation of cell polarity, proliferation, and tissue development. Defects in CD344 expression, or its mutation, lead e.g. to serious failures in retinal vascularization, defects in cerebellum, progressive hearing loss, or impaired corpora lutea formation and function.
ID Covalab | mab21343 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | CH3A4A7 |
Isotype | IgG1 kappa |
Raised in | Mouse |
Immunogen | WERI-RB-1 retinoblastoma cells |
Activity cross reaction | Non-human primates, Human |
Species | Hu |
Labelling | PE |
Form | Purified |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Target | CD344 |
Uniprot ID | Q9ULV1 |
Gene ID | FZD4 |
Applications | FC, IHC |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC : The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
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