Galectin-3 antibody (M3/38)

Galectin-3 (Gal-3)
35 kDa lectin
Carbohydrate-binding protein 35 (CBP 35)
Galactose-specific lectin 3
IgE-binding protein
L-34 galactoside-binding lectin
Laminin-binding protein
Lectin L-29
Mac-2 antigen
Gene name: Lgals3
As low as $640.00
In stock
Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.
More Information
ID Covalab mab21330
Product type Primary antibodies
Clonality Monoclonal antibody
Clone M3/38
Isotype IgG2a kappa
Raised in Rat
Immunogen The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface.
Species Hu, Ms
Labelling None
Form Purified (protein A)
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze.
Target Lgals3
Uniprot ID P16110
Gene ID 16854
Applications FC, ICC, IHC-P, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
FC (2-6 µg/ml)
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