DLL4 antibody (MHD4-46) [PE]

Delta-like protein 4
Drosophila Delta homolog 4 (Delta4)
Gene name: DLL4
As low as $640.00
In stock
Ref
00118930
DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.
More Information
ID Covalab mab21316
Product type Primary antibodies
Clonality Monoclonal antibody
Clone MHD4-46
Isotype IgG1 kappa
Raised in Mouse
Immunogen The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
Activity cross reaction Recombinant soluble human DLL4.
Species Hu
Labelling ACE
Form Purified
Preservative NaN3 15 mM
Storage instructions Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Target DLL4
Uniprot ID Q9NR61
Gene ID 54567
Applications FC
Working dilutions Optimal dilution should be determined by the end user.
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