ALIX antibody

Programmed cell death 6-interacting protein
PDCD6-interacting protein
ALG-2-interacting protein 1
ALG-2 interacting Protein-X
Hp95
Gene name: PDCD6IP, AIP1, ALIX, KIAA1375
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00013156
ALIX belongs to the ESCORT machinery and is involved in multivesicular body (MVB) sorting. This function is used during HIV-1 budding. ALIX is also involved in apoptotic process.
More Information
ID Covalab pab0204
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Recombinant Alix Protein
Activity cross reaction Reacts with human 91-93 kDa Alix protein
Species Hu
Labelling None
Form Antiserum
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.Store reconstituted antibodies at +4°C.For extended periods store in aliquots at -20°C.Antibodies are guaranteed for 6 month from date of receipt.
Target ALIX
Uniprot ID Q8WUM4
Gene ID 10015
Applications ELISA, IF, IHC, WB
Working dilutions Optimal dilution should be determined by the end user. The following are guidelines only :IHC (1:200 - 1:1000)WB (1:200 - 1:1000)
Publication I * Larios J et al. J Cell Biol. 2020 Mar 2;219(3)* Jones S et al. Sci Rep. 2020 Jan 20;10(1):663 (WB)* Lombardi M et al. Acta Neuropathol. 2019 Jul 30. (WB)* Amoruso A et al. J Neuroimmunol. 2018 Oct 15;323:43-48.* Miranda AM et al. Nat Commun. 2018 Jan 18,9(1):291. (WB, Hu)* Williamson RL et al. J Biol Chem. 2017 Oct 11.* Laulagnier K et al. Cell Mol Life Sci. 2017 Sep 27.* Leblanc P et al. Methods Mol Biol. 2017,1545:153-176. (WB)* Kanadome T et al. FEBS J. 2016 Nov 4. doi: 10.1111/febs.13949* Tomas A et al. Nat Commun. 2015 Jun 12,6:7324.* Chassefeyre R et al. J Neurosci. 2015 Feb 18,35(7):3155-73.* Takahashi T et al. Int. Int J Mol Sci. 2015 Feb 6,16(2):3677-99.* Fuerer C et al. J Biol Chem. 2014 Jun 20,289(25):17854-71.* Inuzuka T et al. Biosci Rep. 2013 Mar 7,33(2):e00026.* Pasqual G et al. PLoS Pathog. 2011 Sep,7(9):e1002232. * Ariumi Y et al. PLoS ONE. 2011 Jan,6(1):e14517.* Mahul-Mellier A.L et al. J Neurosci. 2006 Jan 11,26(2):542-9.* Chatellard-Causse C et al. J Biol Chem. 2002 Aug 9,277(32):29108-15.
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