Fatty Acid Synthase (FAS) antibody

Fatty acid synthase
Including the following 7 domains:
1. [Acyl-carrier-protein] S-acetyltransferase
2. [Acyl-carrier-protein] S-malonyltransferase
3. 3-oxoacyl-[acyl-carrier-protein] synthase
4. 3-oxoacyl-[acyl-carrier-protein] reductase
5. 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
6. Enoyl-[acyl-carrier-protein] reductase
7. Oleoyl-[acyl-carrier-protein] hydrolase
Gene name: FASN, Fasn
As low as $640.00
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00096466
FAS (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis (triglyceride production).It is a target for SREBP and is upregulated by LXR activation.Fatty liver is often the result of FAS activation.It is also one of the accepted markers for insulin resistance and SREBP, LXR activation.
More Information
ID Covalab pab50029
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen An internal synthetic peptide, conjugated to KLH, made near the N-terminus of the mouse FAS protein sequence.
Activity cross reaction Reacts with FAS protein from human, pig, rat, mouse, primate, chicken and plants.
Species Chick, Hu, Mk, Ms, Pl, Po, Rat
Labelling None
Form Antiserum
Preservative NaN3 0.05%
Storage instructions Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Target Fatty Acid Synthase
Uniprot ID P19096
Applications ICC, IF, IHC, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
ICC/IF (1:2000)
IHC (1:500)
IP (1:100)
WB (1:1000)
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