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Fibroblast Growth Factor Receptor 1 alpha (FGFR1α) (M2F12) antibody
FGFR-1
Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1
Fms-like tyrosine kinase 2, FLT-2
N-sam
Proto-oncogene c-Fgr
CD_antigen : CD331
CEK
FLG
HH2
OGD
KAL2
HBGFR
HRTFDS
Gene name : FGFR1
Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1
Fms-like tyrosine kinase 2, FLT-2
N-sam
Proto-oncogene c-Fgr
CD_antigen : CD331
CEK
FLG
HH2
OGD
KAL2
HBGFR
HRTFDS
Gene name : FGFR1
As low as
$528.40
In stock
Ref
00096689
Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.
| ID Covalab | mab60176 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | M2F12 |
| Isotype | IgG2a |
| Raised in | Mouse |
| Immunogen | Recombinant human ectodomain of FGFr1α expressed in E. coli beginning with pro23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH terminal glu-phe sequences. |
| Activity cross reaction | Reacts with human Fibroblast Growth Factor Receptor 1 alpha (FGFR1α). Epitope is within the sequence between glu30 and ala74 of FGFr1α. Cross-reacts with mouse and rat protein. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.02% |
| Storage instructions | Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles. |
| Target | Fibroblast Growth Factor Receptor 1 alpha (FGFR1α) |
| Uniprot ID | P11362 |
| Gene ID | 2260 |
| Applications | FC, ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB (1 µ)g/ml FC (1:500 - 1:1000) ICC/IF (10 µg/ml) IHC (1:10 - 1:500) IHC-F (1:10 - 1:500) IP (1:10 - 1:500) |
| Publication | * Feng S, et al. Biochim Biophys Acta. 1996 Jan 10,1310(1):67-73. * Zhao XM, et al. J Clin Invest. 1994 Sep,94(3):992-1003. * Morrison RS, et al. Cancer Res. 1994 May 15,54(10):2794-9. * Prudovsky I, et al. J Biol Chem. 1994 Dec 16,269(50):31720-4. * Xu J, et al. J Biol Chem. 1992 Sep 5,267(25):17792-803. |
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