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Heparanase (HPSE) antibody
Endo-glucoronidase
Heparanase-1 (Hpa1)
Gene name : HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1
Heparanase-1 (Hpa1)
Gene name : HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1
As low as
$306.10
In stock
Ref
00013375
Heparanase facilitates cell migration during tumor invasion (metastasis) and inflammation via extracellular matrix degradation and remodeling
| ID Covalab | pab0232 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from human N terminal region of Heparanase (HPSE) |
| Activity cross reaction | Reacts with human 62 kDa HPSE protein, Heparanase 50 kDa subunit and Heparanase 8 kDa subunit. Cross reacts with mouse, rat and bovine protein due to sequence homology. |
| Species | Hu, Rat |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Heparanase (HPSE) |
| Uniprot ID | Q9Y251 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC (1:100 - 1:500) WB (1:500 - 1:2000) |
| Publication | - Navarro F.P. et al. Brain heparanase expression is up-regulated during postnatal development and hypoxia-induced neovascularization in adult rats. J Neurochem. 2008 Apr;105(1):34-45. |
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