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CD11b antibody
CD11 antigen-like family member B
CR-3 alpha chain
Cell surface glycoprotein MAC-1 subunit alpha
Leukocyte adhesion receptor MO1
Neutrophil adherence receptor, CD11b
Gene name : ITGAM, CD11B, CR3A
CR-3 alpha chain
Cell surface glycoprotein MAC-1 subunit alpha
Leukocyte adhesion receptor MO1
Neutrophil adherence receptor, CD11b
Gene name : ITGAM, CD11B, CR3A
As low as
$323.40
In stock
Ref
00106896
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
| ID Covalab | pab0976-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | recombinant human GST-Integrin alpha-M protein |
| Activity cross reaction | Reacts with human Integrin alpha-M |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Integrin alpha-M |
| Uniprot ID | P11215 |
| Gene ID | 3684 |
| Applications | ELISA, ICC, IF, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: WB (1:500 - 1:2000) ICC/IF (1:200 - 1:1000) |
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