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B-cell lymphoma/leukemia 11B (BCL-11B) antibody
B-cell CLL/lymphoma 11B
COUP-TF-interacting protein 2
Radiation-induced tumor suppressor gene 1 protein (hRit1)
Gene name : BCL11B, CTIP2, RIT1
COUP-TF-interacting protein 2
Radiation-induced tumor suppressor gene 1 protein (hRit1)
Gene name : BCL11B, CTIP2, RIT1
As low as
$306.10
In stock
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00014618
Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element
ID Covalab | pab0574 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic peptide derived from Nter domain of common domain of human BCL-11B and BCL-11A |
Activity cross reaction | Reacts with human 95 kDa protein. Cross reacts with human BCL11A (91 kDa). May cross react with BCL11B & A from mouse and other species, due to the homology. |
Species | Hu |
Labelling | None |
Form | Antiserum |
Preservative | None |
Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
Target | B-cell lymphoma/leukemia 11B (BCL-11B) |
Uniprot ID | Q9C0K0 |
Applications | ELISA, IHC, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - IHC : 1/50 to 1/500 - WB : 1/200 to 1/2 000 |
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