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Charged multivesicular body protein 3 (CHMP3) antibody
Chromatin-modifying protein 3
Neuroendocrine differentiation factor (hVps24)
Gene name: CHMP3, CGI149, NEDF, VPS24
Neuroendocrine differentiation factor (hVps24)
Gene name: CHMP3, CGI149, NEDF, VPS24
As low as
$306.10
In stock
Ref
00014094
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.
| ID Covalab | pab0710 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from internal domain of human Vps24 protein |
| Activity cross reaction | Reacts with human 25 kDa hVps24. May cross-react with protein from mouse, rat and other species due to sequence homology. |
| Species | Hu |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Charged multivesicular body protein 3 |
| Uniprot ID | Q9Y3E7 |
| Gene ID | 51652 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: IHC 1:200 - 1:2000 WB 1:500 - 1:2000 |
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