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HIF-1 beta antibody (H1beta234)
Aryl hydrocarbon receptor nuclear translocator
(ARNT protein)
Class E basic helix-loop-helix protein 2 (bHLHe2)
Dioxin receptor, nuclear translocator
Hypoxia-inducible factor 1-beta (HIF-1-beta), (HIF1-beta)
Gene name: ARNT, BHLHE2
(ARNT protein)
Class E basic helix-loop-helix protein 2 (bHLHe2)
Dioxin receptor, nuclear translocator
Hypoxia-inducible factor 1-beta (HIF-1-beta), (HIF1-beta)
Gene name: ARNT, BHLHE2
As low as
$528.40
In stock
Ref
00028910
HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits which are bHLH proteins of PAS (PER, ARNT, SIM) family. HIF-1 beta forms heterodimer with AHR, AHRR, HIF1 alpha and EPAS1/HIF2 alpha as well as with other bHLH proteins and its dimerization is required for efficient DNA binding. Interact with TACC3 and NOCA7.
| ID Covalab | mab50050 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | H1beta234 |
| Isotype | IgG1 / Kappa |
| Raised in | Mouse |
| Immunogen | Fusion protein containing amino acids 496-789 of human HIF-1 beta |
| Activity cross reaction | Reacts with human HIF 1 beta /ARNT. Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species. |
| Species | Bov, Ft, Hu, Mk, Ms, Po, Rat, Sh |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.05% |
| Storage instructions | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Target | Hypoxia-inducible factor 1-beta |
| Uniprot ID | P27540 |
| Gene ID | 405 |
| Applications | ChIP, GS, IHC, IHC - P, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: ChIP 1:10-1:500, IHC 1:100, IHC-P 1:100, WB 1:500 |
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