DNA polymerase epsilon subunit 3 antibody

Arsenic-transactivated protein (AsTP)
Chromatin accessibility complex 17 kDa protein (CHRAC-17), (HuCHRAC17)
DNA polymerase II subunit 3
DNA polymerase epsilon subunit p17
Gene name: POLE3, CHRAC17
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00024781
Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
More Information
ID Covalab mab50048
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 3C5.1
Isotype IgG2a
Raised in Mouse
Immunogen Human DNA Polymerase epsilon purified from HeLa cells
Activity cross reaction Reacts with DNA polymerase epsilon from human mouse, monkey, mink and hamster. Does not recognize DNA pol alpha, beta or delta. Does not reacts with Drosophilia or baculovirus host cell pol epsilon, and weakly, if at all, on S. cerivisae pol epsilon.
Species Hu, Mk, Ms
Labelling None
Form Purified (protein G)
Preservative None
Storage instructions Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Target DNA polymerase epsilon subunit 3
Uniprot ID Q9NRF9
Gene ID 54107
Applications ICC, IF, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF 1:100,
IP 1:10-1:500,
WB 5 ug/ml
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