NPPB antibody

Natriuretic peptides B
Gamma-brain natriuretic peptide
Brain natriuretic peptide 32, BNP(1-32), BNP-32, BNP(1-30), BNP(1-29), BNP(1-28), BNP(2-31), BNP(3-32), BNP(3-30), BNP(3-29), BNP(4-32), BNP(4-31), BNP(4-30), BNP(4-29), BNP(4-27), BNP(5-32), BNP(5-31), BNP(5-29)
Gene name : NPPB
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00106890
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
More Information
ID Covalab pab0975-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide of derived from C terminal part of human NPPB.
Activity cross reaction Reacts with human NPPB. Cross react with monkeys protein due to sequence homology.
Species Hu, Mk
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target NPPB
Uniprot ID P16860
Gene ID 4879
Applications ELISA, ICC, IF, WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000
- ICC, IF: 1/200 to 1/1000
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