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hnRNP C1/C2 antibody (4F4)
Heterogeneous nuclear ribonucleoproteins C1/C2
Gene name : HNRNPC, HNRPC
Gene name : HNRNPC, HNRPC
As low as
$463.20
In stock
Ref
00106733
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
| ID Covalab | mab0138-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 4F4 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | RNPs eluted from oligo(dT) cellulose column |
| Activity cross reaction | Reacts with hnRNP -C1/C2 from human, monkey, hamster and chicken. |
| Species | Chick, Ham, Hu, Mk |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | NaN3 15 mM |
| Storage instructions | For continuous use, store antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | hnRNP C1/C2 |
| Uniprot ID | P07910 |
| Gene ID | 3183 |
| Applications | ELISA, ICC, IF, IHC - P, IP, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only : WB (0.1 - 0.2 µg/ml) |
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