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Beta-Lactamase (8A5.A10) antibody
Beta-lactamase TEM
IRT-4
Penicillinase
TEM-1, TEM-16/CAZ-7, TEM-2, TEM-24/CAZ-6, TEM-3, TEM-4, TEM-5, TEM-6, TEM-8/CAZ-2
Gene name: bla, blaT-3, blaT-4, blaT-5, blaT-6
IRT-4
Penicillinase
TEM-1, TEM-16/CAZ-7, TEM-2, TEM-24/CAZ-6, TEM-3, TEM-4, TEM-5, TEM-6, TEM-8/CAZ-2
Gene name: bla, blaT-3, blaT-4, blaT-5, blaT-6
As low as
$623.20
In stock
Ref
00096557
The beta-lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta-lactams are structurally related through the presence of a core beta-lactam ring. Bacterial resistance to beta-lactams continues to increase, primarily due to microbial production of beta-lactamases. Beta-lactamases catalyze the hydrolysis of the beta-lactam bond which destroys anti-bacterial activity. Bacteria the produce TEM- or SHV-type beta-lactamases have point mutations in structural genes that have extended the substrate specificity of these betalactamases. As a result, many of the beta-lactamase-producing Gram-negative bacteria have become multi-drug resistant.
| ID Covalab | mab60044 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 8A5.A10 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | 5’-His-tagged E. coli 205 TEM-1 R+ beta-lactamase, accession no. P62593 |
| Activity cross reaction | Reacts with Escherichia coli Beta-Lactamase. |
| Species | E. coli |
| Labelling | None |
| Form | Purified |
| Preservative | None |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | Beta-Lactamase |
| Uniprot ID | P62593 |
| Gene ID | 2716540 |
| Applications | ELISA, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB 10 µg/ml ELISA 10 - 20 µg/ml |
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