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Beta-Lactamase (3E11.G3) antibody
Beta-lactamase
Cephalosporinase
Gene nam: ampC
E. cloacae
Cephalosporinase
Gene nam: ampC
E. cloacae
As low as
$1,381.80
In stock
Ref
00096556
The beta-lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta-lactams are structurally related through the presence of a core beta-lactam ring. Bacterial resistance to beta-lactams continues to increase, primarily due to microbial production of beta-lactamases. Beta-lactamases catalyze the hydrolysis of the beta-lactam bond which destroys anti-bacterial activity. Bacteria the produce TEM- or SHV-type beta-lactamases have point mutations in structural genes that have extended the substrate specificity of these betalactamases. As a result, many of the beta-lactamase-producing Gram-negative bacteria have become multi-drug resistant. Beta-lactamase from Enterobacter cloacae is a serine beta-lactamase with substrate specificity for cephalosporins.
ID Covalab | mab60043 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | 3E11.G3 |
Isotype | IgG3 |
Raised in | Mouse |
Immunogen | Type IV beta lactamase from Enterobacter cloacae, accession no. P05364. |
Activity cross reaction | Reacts with Type IV betalactamase of Enterobacter cloacae. |
Species | Ent |
Labelling | None |
Form | Purified |
Preservative | None |
Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
Target | Beta-Lactamase |
Uniprot ID | P05364 |
Applications | ELISA |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: ELISA 10 - 20 µg/ml (optimized for beta-lactamase on solid phase at 10 µg/ml). |
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