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ADAMTS4 (Metalloprotease Domain) antibody
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4)
ADMP-1
Aggrecanase-1
Gene name : ADAMTS4, KIAA0688
ADAMTS-2
ADMP-1
Aggrecanase-1
Gene name : ADAMTS4, KIAA0688
ADAMTS-2
As low as
$573.50
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00015651
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
| ID Covalab | pab70258 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic 16 amino acid peptide from Metalloprotease domain of human ADAMTS4. Percent identity with other species by BLAST analysis: Human (100%), Orangutan (100%), Gibbon (100%), Marmoset (100%), Panda (100%), Dog (100%), Bat (100%), Horse (100%) |
| Activity cross reaction | Reacts with human ADAMTS4. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Species | Hu |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.1% |
| Storage instructions | Long term: -70°C; Short term: +4°C |
| Target | ADAMTS4 |
| Accession Number | O75173 |
| Applications | IHC - P |
| Working dilutions | IHC - P (4 ) |
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