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Keratinocyte Transglutaminase (TG1) (hu)
Transglutaminase 1 (TG1)
Protein-glutamine gamma-glutamyltransferase K
Epidermal TGase
Transglutaminase K (TG(K)), (TGK), (TGase K)
Gene name : TGM1, KTG
Protein-glutamine gamma-glutamyltransferase K
Epidermal TGase
Transglutaminase K (TG(K)), (TGK), (TGase K)
Gene name : TGM1, KTG
As low as
$534.82
In stock
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00038962
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum
| ID Covalab | opr0028 |
|---|---|
| Uniprot ID | P22735 |
| Target | Transglutaminase-1 (TGase-1) |
| Storage instructions | Store working aliquots at a minimum of -20°C Avoid repeated freezing and thawing Delivery at ambient temperature is possible |
| Description | His6-rhTG1 is based on the TGM1-allele from I.M.A.G.E.-clone IRAKp961M1628 isolated from human skin squamous cell carcinoma. It is N-terminally fused to a hexahistidine-tag resulting in the encoded N-terminal amino acid sequence MHHHHHHMDGPR. His6-rhTG1 is purified by IMAC to more than 90 % purity. |
| Raised in | E. coli |
| Species | Hu |
| Form | Recombinant |
| Gene ID | 7051 |
| Labelling | His-Tag |
| Preparation method | Add 10 mM Ca2+ to activate His6-rhTG1. |
| Poids moléculaire | 90 kDa |
| Principe | His6-rhTG1 catalyzes acyl transfer reactions from glutamin residues in proteins or peptides to primary amines, e. g. the formation of ε-(γ-glutamyl) lysine bonds between proteins by transferring the acyl group of a peptide-bound glutamine residue to the primary amino group of a peptide-bound lysine residue. His6-rhTG1 may also be used for immunoprecipitation. |
| Pureté | > 90 % (visually by SDS-PAGE) |
| Product type | Proteins |
| Applications | FA, IP |
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