Pyruvate dehydrogenase kinase (PDK1) antibody

Pyruvate dehydrogenase kinase, PDK1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial
Pyruvate dehydrogenase kinase isoform 1, PDH kinase 1
Gene name: PDK1, PDHK1
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00035675
Pyruvate dehydrogenase kinase isoform 1 (PDK1) inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
More Information
ID Covalab pab50211
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide made to a C-Terminal portion of the human PDK1 protein sequence (between residues 350-436)
Activity cross reaction Reacts with the human, mouse, rat PDK1. Predicted to cross react with chicken (93%).
Species Hu, Ms, Rat
Labelling None
Form Purified
Preservative NaN3 0.05%
Storage instructions Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Target Pyruvate dehydrogenase kinase, PDK1
Uniprot ID Q15118
Gene ID 5163
Applications ICC, IF, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
ICC/IF (1:1000-1:2000)
WB (2 µg/ml)
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