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G protein-activated inward rectifier potassium channel 1 (GIRK-1) antibody
Inward rectifier K(+) channel Kir3.1
Potassium channel, inwardly rectifying subfamily J member 3
Gene name : KCNJ3, GIRK1
Potassium channel, inwardly rectifying subfamily J member 3
Gene name : KCNJ3, GIRK1
As low as
$306.10
In stock
Ref
00014170
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
| ID Covalab | pab0322 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from Cter domain of GIRK-1 protein |
| Activity cross reaction | Reacts with human 56 kDa GIRK-1 protein. Cross reacts with protein from mouse, rat and other species due to sequence homology. |
| Species | Hu |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | G protein-activated inward rectifier potassium channel 1 (GIRK-1) |
| Uniprot ID | P48549 |
| Gene ID | 3760 |
| Applications | ELISA, IF, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IF 1:200 - 1:1000 WB 1:500 - 1:5000 |
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