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ACVR1 / ALK2 (Internal) antibody
Activin receptor type-1
Activin receptor type I (ACTR-I)
Activin receptor-like kinase 2 (ALK-2)
Serine/threonine-protein kinase receptor R1 (SKR1)
TGF-B superfamily receptor type I (TSR-I)
ACVR1, Activin A receptor type I, Activin A receptor-like kinase 2, Actr1, ACTRI, ActRIA, ACVR1A, ACVRLK2, ALK2, FOP, Tsk7L, TSRI
Activin receptor type I (ACTR-I)
Activin receptor-like kinase 2 (ALK-2)
Serine/threonine-protein kinase receptor R1 (SKR1)
TGF-B superfamily receptor type I (TSR-I)
ACVR1, Activin A receptor type I, Activin A receptor-like kinase 2, Actr1, ACTRI, ActRIA, ACVR1A, ACVRLK2, ALK2, FOP, Tsk7L, TSRI
As low as
$628.00
In stock
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00020288
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis.
Involved in BMP signaling pathway.
Involved in BMP signaling pathway.
| ID Covalab | pab72611 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Goat |
| Immunogen | Synthetic peptide C-RKFKRRNQERLNPRD from an internal region of human ACVR1 / ALK2 (NP_001096.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (100%) |
| Activity cross reaction | Reacts with human ACVR1 / ALK2. Cross reacts with canine, mouse and rat protein. |
| Species | Ca, Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store at -20°C. Minimize freezing and thawing. |
| Target | ACVR1 / ALK2 |
| Accession Number | Q04771 |
| Applications | ELISA, IHC - P, WB |
| Working dilutions | ELISA (1:128000), IHC-P (4 µg/ml), WB (0.3 - 1 µg/ml) |
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