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Galectin-3 antibody (M3/38)
Galectin-3 (Gal-3)
35 kDa lectin
Carbohydrate-binding protein 35 (CBP 35)
Galactose-specific lectin 3
IgE-binding protein
L-34 galactoside-binding lectin
Laminin-binding protein
Lectin L-29
Mac-2 antigen
Gene name: Lgals3
35 kDa lectin
Carbohydrate-binding protein 35 (CBP 35)
Galactose-specific lectin 3
IgE-binding protein
L-34 galactoside-binding lectin
Laminin-binding protein
Lectin L-29
Mac-2 antigen
Gene name: Lgals3
As low as
€407.80
In stock
Ref
00119496
Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.
ID Covalab | mab21330 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | M3/38 |
Isotype | IgG2a kappa |
Raised in | Rat |
Immunogen | The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface. |
Species | Hu, Ms |
Labelling | None |
Form | Purified (protein A) |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Do not freeze. |
Target | Lgals3 |
Uniprot ID | P16110 |
Gene ID | 16854 |
Applications | FC, ICC, IHC-P, IP, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC (2-6 µg/ml) |
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