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CD235a antibody (JC159) [Biotin]
Glycophorin-A
MN sialoglycoprotein
PAS-2
Sialoglycoprotein alpha
CD235a
Gene name: GYPA, GPA
MN sialoglycoprotein
PAS-2
Sialoglycoprotein alpha
CD235a
Gene name: GYPA, GPA
As low as
€499.70
In stock
Ref
00119301
CD235a (Glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to glycophorin B (GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, an Streptococcus adhesin.
ID Covalab | mab21324 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | JC159 |
Isotype | IgG1 |
Raised in | Mouse |
Immunogen | The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B. |
Activity cross reaction | Membrane preparation from splenic hairy cell leukemia |
Species | Hu, Rat |
Labelling | Biotin |
Form | Purified |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
Target | CD235a |
Uniprot ID | P02724 |
Gene ID | 2993 |
Applications | FC, IHC-F, IHC-P |
Working dilutions | Optimal dilution should be determined by the end user. FC (1-4 µg/ml) |
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