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Prokineticin 2 (PK2/Bv8) antibody
Prokineticin-2, PK2
Protein Bv8 homolog
Gene name : PROK2, BV8, HH4, KAL4, MIT1
Protein Bv8 homolog
Gene name : PROK2, BV8, HH4, KAL4, MIT1
As low as
€294.00
In stock
Ref
00110186
Prokineticins belong to a family of highly conserved small peptides discovered a decade ago in frog skin and snake venon. The mammalian orthologs consist in two prokineticins peptides: prokineticin 1 (PK1) and prokineticin 2 (PK2), signaling through two receptors: prokineticin receptor 1 (PK-R1) and prokineticin receptor 2 (PK-R2).
ID Covalab | pab0409-P |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic peptide derived from Cter region of human PK2 |
Activity cross reaction | Reacts with human 14 kDa PK2.Cross reacts with proteins from mouse, rat and other species |
Species | Bov, Hu, Ms, Rat |
Labelling | None |
Form | Purified (protein A) |
Preservative | None |
Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
Target | Prokineticin 2 |
Uniprot ID | Q9HC23 |
Gene ID | 60675 |
Applications | ELISA, ICC, IHC - F, IHC - P, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ICC/ IHC (1:50 - 1:1000) WB (1:200 - 1:1000) |
Publication | - Abou-Hamdan M. et al. Critical role for prokineticin 2 in CNS autoimmunity. Neurol Neuroimmunol Neuroinflamm 2015;2:e95 (IHC-F) - Lauttia S et al. Prokineticins and Merkel cell polyomavirus infection in Merkel cell carcinoma. Br J Cancer. 2014 Feb 4.(IHC-P, Hu) - Keramidas M et al. Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells. J Endocrinol. 2008 Mar;196(3):473-82.(IHC-P, ICC, Bov) - Hoffmann P et al. Expression and oxygen regulation of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 and its receptors in human placenta during early pregnancy. Endocrinology. 2006 Apr:147(4):1675-84. (IHC-P, Hu, Ms) |
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