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NKp80 antibody (5D12)
Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1)
Activating coreceptor NKp80
C-type lectin domain family 5 member C
Gene name: KLRF1, CLEC5C, ML
Activating coreceptor NKp80
C-type lectin domain family 5 member C
Gene name: KLRF1, CLEC5C, ML
As low as
€407.80
In stock
Ref
00119591
NKp80, also known as CLEC5C or KLRF1, is a type II transmembrane glycoprotein of the C lectin family, which is expressed in 80 kDa homodimers on NK cells, and subsets of CD8+ alpha/beta T cells, and gamma/delta T cells. It belongs to the activating coreceptors, which induce cytotoxicity, and production of pro-inflammatory cytokines. Its ligand AICL is expressed on myeloid cells.
ID Covalab | mab21334 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | 5D12 |
Isotype | IgG1 kappa |
Raised in | Mouse |
Immunogen | The mouse monoclonal antibody 5D12 recognizes an extracellular epitope of human NKp80 (CLEC5C), a C-type lectin family member, expressed on NK cells and subsets of T cells. |
Species | Hu, Mk |
Labelling | None |
Form | Purified (protein A) |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Do not freeze. |
Target | NKp80 |
Uniprot ID | Q9NZS2 |
Gene ID | 51348 |
Applications | FC, IP |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC (1-4 µg/ml) |
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