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SARS-CoV-2 Spike RBD – HEK – his tag (Mutation 501Y.V2) - SA
Spike glycoprotein (S glycoprotein)
E2
eplomer protein
Gene name: S
E2
eplomer protein
Gene name: S
As low as
€569.90
In stock
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00119277
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019 nCoV (2019 Novel Coronavirus) is an enveloped, single, and positive-stranded RNA virus. The virus encodes four major structural proteins that have played important roles in causing the infection: Spike protein (S protein), nucleocapsid protein (N protein), membrane protein (M protein), and small envelope protein (E protein).
S1 sub-unit binds via its RBD (Receptor Binding Domain) to the cellular receptor angiotensin-converting enzyme 2 (ACE2) and active S2 sub-unit fuses to the viral membranes with the host cell membrane. The spike protein is reported to induce the neutralizing-antibody and T-cell responses, as well as protective immunity. The CoV spike (S) glycoprotein therefore represent the key target for vaccines, therapeutic antibodies, and diagnostics.
S1 sub-unit binds via its RBD (Receptor Binding Domain) to the cellular receptor angiotensin-converting enzyme 2 (ACE2) and active S2 sub-unit fuses to the viral membranes with the host cell membrane. The spike protein is reported to induce the neutralizing-antibody and T-cell responses, as well as protective immunity. The CoV spike (S) glycoprotein therefore represent the key target for vaccines, therapeutic antibodies, and diagnostics.
ID Covalab | CovID190009 |
---|---|
Target | SARS-CoV-2 Spike Protein (RBD) <br/>Mutation 501Y.V2 (K417N-E484K-N501Y - South Africa) |
Storage instructions | The product can be stored at -20°C or below. Avoid repeated freezing and thawing cycles. The shelf life of the product is unspecified. |
Description | SARS CoV-2 recombinant Spike (S) protein (receptor-binding domain, RBD), mutations K417N-E484K-N501Y, C-terminal hexa-His-Tag (HEK cells). |
Raised in | HEK cells |
Species | SARS-CoV-2 |
Form | Recombinant Protein |
Labelling | His-tag |
Pureté | > 90% as analyzed by SDS-PAGE |
Product type | Proteins |
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