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ADAM17 (aa807-823) antibody

Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17)
Snake venom-like protease
TNF-alpha convertase
TNF-alpha-converting enzyme
CD156b
ADAM18, MGC71942, Tumor necrosis factor alpha converting enzyme
Gene name : ADAM17, CSVP, TACE
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway

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€360.00
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Ref : 00015637

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Product Code pab70244
Immunogen Synthetic peptide from human ADAM17.
Target Specificity Reacts with human TACE. Cross reacts with mouse and rat protein.
Name ADAM17
Accession Number P78536
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage +4°C or -20°C, Avoid repeated freezing and thawing.
Applications Western Blot, IHC - Paraffin sections
Working dilutions IHC - P (20 µg/ml), WB
Research areas Cytoskeleton,Immunology,Signal transduction
Print datasheet

IHC : ADAM17 (aa807-823) antibody<br/>(pab70244)<br/>Anti-ADAM17 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 µg/ml.

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