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ACVR2A (N-Terminus) antibody
Activin receptor type-2A, Activin receptor type IIA, ACTR-II, AACTRIIA
Gene name: ACVR2A, ACVR2
Activin A receptor type II, ACTRII
Gene name: ACVR2A, ACVR2
Activin A receptor type II, ACTRII
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00028649
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
ID Covalab | pab75300 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | KLH conjugated synthetic peptide between 2-29 amino acids from the N-terminal region of human ACVR2A. |
Activity cross reaction | Reacts with human and mouse ACVR2A. Predicted to cross reacts with Rat, Chicken, Cow. |
Species | Hu, Ms |
Labelling | None |
Form | Purified |
Preservative | 0.09% NaN3 |
Storage instructions | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Target | ACVR2A |
Uniprot ID | P27037 |
Gene ID | 92 |
Applications | IHC - P, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: IHC-P (5 µg/ml) WB (1:100 - 1:500) |
Publication | * Reichel C et al. Drug Test Anal. 2017 Nov 28. |
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