SARS-CoV-2 Spike S1 Subunit – HEK – his tag

Spike glycoprotein (S glycoprotein)
E2
eplomer protein
Gene name: S
As low as €345.00
In stock
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00118729
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019 nCoV (2019 Novel Coronavirus) is an enveloped, single, and positive-stranded RNA virus. The virus encodes four major structural proteins that have played important roles in causing the infection: Spike protein (S protein), nucleocapsid protein (N protein), membrane protein (M protein), and small envelope protein (E protein).

S1 sub-unit binds via its RBD (Receptor Binding Domain) to the cellular receptor angiotensin-converting enzyme 2 (ACE2) and active S2 sub-unit fuses to the viral membranes with the host cell membrane. The spike protein is reported to induce the neutralizing-antibody and T-cell responses, as well as protective immunity. The CoV spike (S) glycoprotein therefore represent the key target for vaccines, therapeutic antibodies, and diagnostics.
More Information
ID Covalab CovID190002
Uniprot ID P59594
Target Spike S1 glycoprotein
Storage instructions The product can be stored at -20°C or below. Avoid repeated freezing and thawing cycles. The shelf life of the product is unspecified.
Description SARS CoV-2 recombinant Spike (S) protein S1-Subunit, amino acids 13-685, C-terminal hexa-His-Tag (HEK cells).
Raised in HEK cells
Species SARS-CoV-2
Form Recombinant Protein
Labelling His-tag
Poids moléculaire ~79 kDa (predicted)
Pureté > 85% as analyzed by SDS-PAGE
Product type Proteins
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