Ly6G antibody (RB6-8C5) [FITC]

Lymphocyte antigen 6G, Ly-6G
Ly-6G.1
Gene name: Ly6g
As low as €260.20
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00114925
Ly6G antibody (RB6-8C5) [FITC]
More Information
ID Covalab mab21177
Product type Primary antibodies
Clonality Monoclonal antibody
Clone RB6-8C5
Isotype IgG2b
Raised in Rat
Immunogen Murine granulocytes
Activity cross reaction Reacts with mouse Ly6G.
Species Ms
Labelling FITC
Form Purified
Preservative NaN3 15 mM
Storage instructions Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Target Ly6G
Uniprot ID P35461
Gene ID 546644
Applications FA, FC, IHC, IP, WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
FC (1 µg/ml)
Publication *Jung YW et al. MMP induced by Gr-1+ cells are crucial for recruitment of Th cells into the airways. Eur J Immunol. 2009 Aug,39(8):2281-92.
* Leendertse M et al. Neutrophils are essential for rapid clearance of Enterococcus faecium in mice. Infect Immun. 2009 Jan,77(1):485-91.
* dos Santos MS et al. Leishmania major: recruitment of Gr-1+ cells into draining lymph nodes during infection is important for early IL-12 and IFN gamma production. Exp Parasitol. 2008 Jul,119(3):403-10.
* Fan J et al. Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling. J Immunol. 2007 May 15,178(10):6573-80.
* Koo GC, Gan YH: The innate interferon gamma response of BALB/c and C57BL/6 mice to in vitro Burkholderia pseudomallei infection. BMC Immunol. 2006 Aug 18,7:19.
* Nagendra S, Schlueter AJ. Absence of cross-reactivity between murine Ly-6C and Ly-6G. Cytometry A. 2004 Apr,58(2):195-200.
* Brown CR et al. Susceptibility to experimental Lyme arthritis correlates with KC and monocyte chemoattractant protein-1 production in joints and requires neutrophil recruitment via CXCR2. J Immunol. 2003 Jul 15,171(2):893-901.
* Fleming TJ et al. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J Immunol. 1993 Sep 1,151(5):2399-408.
* Stoppacciaro A et al. Regression of an established tumor genetically modified to release granulocyte colony-stimulating factor requires granulocyte-T cell cooperation and T cell-produced interferon gamma. J Exp Med. 1993 Jul 1,178(1):151-61.
* Hestdal K et al. Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells. J Immunol. 1991 Jul 1,147(1):22-8.
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