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Amyloid Oligomer αβ antibody
As low as
€600.00
In stock
Ref
00098045
Amyloid monomeric proteins can oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of nondisease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibers. These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer’s symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson’s disease, and accumulation of polyglutamine-containing aggregates in Huntington’s disease.
| ID Covalab | pab60339 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic molecular mimic of soluble oligomers. |
| Activity cross reaction | Reacts with a peptide backbone epitope that is common to all types of amyloid oligomers but is not found in native proteins, amyloidogenic monomers, or mature amyloid fibrils. |
| Species | No |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.09% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | Amyloid Oligomer αβ |
| Applications | DB, ELISA, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: DB (0.5 - 1 µg/ml) WB (0.5 - 1 µg/ml) ELISA (1 - 10 µg/ml) |
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