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Toll-like Receptor 8 (TLR8) antibody
Toll-like Receptor 8, TLR8
Toll like receptor 8
CD288
Gene name: TLR8
Toll like receptor 8
CD288
Gene name: TLR8
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00098034
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
| ID Covalab | pab60328 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide corresponding to an internal region of human TLR8. |
| Activity cross reaction | Reacts with human and mouse TLR8. Do not cross react with TLR7. |
| Species | Hu, Ms |
| Labelling | None |
| Form | Purified |
| Preservative | 0.01% NaN3 |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -70°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Toll-like Receptor 8, TLR8 |
| Uniprot ID | Q9NR97 |
| Gene ID | 51311 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1:500 - 1:2000) ELISA (1:2000 - 1:10000) IHC-P (5 ug/ml). |
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