p53DINP1 antibody

Tumor protein p53-inducible nuclear protein 1
Stress-induced protein
p53-dependent damage-inducible nuclear protein 1, p53DINP1
Gene name: TP53INP1, P53DINP1, SIP
As low as €671.00
In stock
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.
More Information
ID Covalab pab60247
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Peptide corresponding to aa 1-14 of human p53DINP1. This sequence is identical in p53DINP1 α and β and differs from that of mouse p53DINP1 by one amino acid.
Activity cross reaction Reacts with human p53DINP1. Cross-reacts with mouse and rat protein.
Species Hu, Ms, Rat
Labelling None
Form Purified
Preservative NaN3 0.02%
Storage instructions Store in aliquots at -20°C.
Antibodies are guaranteed for 6 months from date of receipt.
Target p53DINP1
Uniprot ID Q96A56
Gene ID 94241
Applications WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB: 1-2 µg/ml
Positive control Human lung tissue
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