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p53DINP1 antibody
Tumor protein p53-inducible nuclear protein 1
Stress-induced protein
p53-dependent damage-inducible nuclear protein 1, p53DINP1
Gene name: TP53INP1, P53DINP1, SIP
Stress-induced protein
p53-dependent damage-inducible nuclear protein 1, p53DINP1
Gene name: TP53INP1, P53DINP1, SIP
As low as
€587.00
In stock
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00097953
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.
| ID Covalab | pab60247 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Peptide corresponding to aa 1-14 of human p53DINP1. This sequence is identical in p53DINP1 α and β and differs from that of mouse p53DINP1 by one amino acid. |
| Activity cross reaction | Reacts with human p53DINP1. Cross-reacts with mouse and rat protein. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt. |
| Target | p53DINP1 |
| Uniprot ID | Q96A56 |
| Gene ID | 94241 |
| Applications | WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: WB: 1-2 µg/ml |
| Positive control | Human lung tissue |
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