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DC-SIGN (Extracellular Domain) antibody
CD209 antigen
C-type lectin domain family 4 member L
Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1
CD209
Gene name: CD209, CLEC4L
C-type lectin domain family 4 member L
Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1
CD209
Gene name: CD209, CLEC4L
As low as
€669.90
In stock
Ref
00097808
DC-SIGN is a dendritic cell receptor that can capture and transport HIV from mucosal areas to remote lymph nodes where HIV is then transferred to CD4+ T lymphocytes. Multiple strains of HIV-1, HIV-2, and SIV bind to dendritic cells via DC-SIGN. DC-SIGN is expressed in mucosal tissues, placenta, small intestine, and rectum.
| ID Covalab | pab60102 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Peptide corresponding to aa 277-293 of human DC-SIGN. |
| Activity cross reaction | Reacts with the extracellular domain of human DC-SIGN (ED). |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt. |
| Target | DC-SIGN |
| Uniprot ID | Q9NNX6 |
| Gene ID | 30835 |
| Applications | WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: WB 1 - 2 µg/ml |
| Positive control | Human placenta tissue lysate |
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