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ARC (N-Terminus) antibody
Nucleolar protein 3
Apoptosis repressor with CARD
Muscle-enriched cytoplasmic protein, Myp
Nucleolar protein of 30 kDa, Nop30
Gene name: NOL3, ARC, NOP, FCM,
Apoptosis repressor with CARD
Muscle-enriched cytoplasmic protein, Myp
Nucleolar protein of 30 kDa, Nop30
Gene name: NOL3, ARC, NOP, FCM,
As low as
€671.00
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00097732
A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The mRNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
| ID Covalab | pab60026 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Peptide corresponding to aa 2-18 of human ARC. |
| Activity cross reaction | Reacts with the human, mouse, and rat ARC. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | ARC |
| Uniprot ID | O60936 |
| Gene ID | 8996 |
| Applications | WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (2 µg/ml) |
| Positive control | HeLa cells |
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