ARC (C-Terminus) antibody

Nucleolar protein 3
Apoptosis repressor with CARD
Muscle-enriched cytoplasmic protein, Myp
Nucleolar protein of 30 kDa, Nop30
Gene name: NOL3, NOP
As low as €610.00
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00097731
A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
More Information
ID Covalab pab60025
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Peptide corresponding to aa 191-208 of human ARC.
Activity cross reaction Reacts with human ARC.
Species Hu
Labelling None
Form Purified
Preservative NaN3 0.02%
Storage instructions Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Target ARC
Uniprot ID O60936
Gene ID 8996
Applications IHC - P, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC (5 µg/ml)
WB (1 - 10 µg/ml)
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