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AIF (C-Terminus) antibody
Apoptosis-inducing factor 1, mitochondrial
Programmed cell death protein 8
Gene name: AIFM1, AIF, PDCD8
Programmed cell death protein 8
Gene name: AIFM1, AIF, PDCD8
As low as
€662.20
In stock
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00097714
A novel protein that causes chromatin condensation and DNA fragmentation has been designated Apoptosis Inducing Factor (AIF). AIF localizes in mitochondria and translocates to the nucleus when apoptosis is induced. This event is followed by the release of chytochrome c and caspase-9 from mitochondria. AIF is highly conserved between human and mouse and widely expressed in different cell types and tissues.
| ID Covalab | pab60008 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Peptide corresponding to aa 593- 606 at the C-terminus of human AIF. This sequence is identical to those of mouse and rat AIF. |
| Activity cross reaction | Reacts with the C-terminus part of human AIF. Cross-reacts with mouse and rat protein. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt. |
| Target | Apoptosis-inducing factor, AIF |
| Uniprot ID | O95831 |
| Gene ID | 9131 |
| Applications | ICC, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: ICC 5 µg/ml WB 0.5 - 2 µg/ml |
| Positive control | K562 cells |
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