p53 (PAb1801) antibody

Cellular tumor antigen p53
Antigen NY-CO-13
Phosphoprotein p53
Tumor suppressor p53
Gene name: TP53, P53
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00096903
p53 is a DNA-binding, cell cycle-regulating transcription factor that governs cell division. It plays a critical role in tumor suppression and has been referred to as “the guardian angel gene” or “the master watchman”. Defects in p53 are linked to >50% of human cancers and restoring p53 function to cancer cells can induce growth arrest and apoptosis. Damaged p53 can also lead to autoimmune disorders.
More Information
ID Covalab mab60390
Product type Primary antibodies
Clonality Monoclonal antibody
Clone PAb1801
Isotype IgG1
Raised in Mouse
Immunogen Fusion protein corresponding to aa 46-53 of human p53.
Activity cross reaction Reacts with human p53.
Species Hu
Labelling None
Form Purified (protein A)
Preservative NaN3 0.09%
Storage instructions Store at -20°C. Avoid repeated freezing and thawing.
Antibodies are guaranteed for 6 months from date of receipt.
Target p53
Uniprot ID P04637
Gene ID 7157
Applications ChIP, ELISA, FC, ICC, IHC, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA, WB (1:1000 - 1:2000)
IHC (1:100 - 1:250)
IP (10 µg/mg of lysate)
FC (1 µg/10^6 cells)
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