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MLL p320 (N4.4) antibody
Histone-lysine N-methyltransferase 2A, Lysine N-methyltransferase 2
ALL-1
CXXC-type zinc finger protein 7
Myeloid/lymphoid or mixed-lineage leukemia
Myeloid/lymphoid or mixed-lineage leukemia protein 1
Trithorax-like protein
Zinc finger protein HRX
Gene name: KMT2A, ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1
ALL-1
CXXC-type zinc finger protein 7
Myeloid/lymphoid or mixed-lineage leukemia
Myeloid/lymphoid or mixed-lineage leukemia protein 1
Trithorax-like protein
Zinc finger protein HRX
Gene name: KMT2A, ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1
As low as
€514.00
In stock
Ref
00096859
MLL (Mixed Lineage Leukemia) is a proto-oncogene that is mutated in a variety of acute leukemias. MLL is proteolytically processed into 2 fragments, MLL N and MLL C, that display opposite transcriptional properties. Processed MLL N and MLL C associate with each other via N-terminal and C-terminal intramolecular interaction domains
| ID Covalab | mab60346 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | N4.4 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Maltose-binding fusion protein containing MLL amino acids 161-356 (N terminal) |
| Activity cross reaction | Reacts with human and mouse MLL p320 |
| Species | Hu, Ms |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | None |
| Storage instructions | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | MLL cleavage product N320, N-terminal cleavage product of 320 kDa, p320 |
| Uniprot ID | Q03164 |
| Gene ID | 4297 |
| Applications | IP, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: IP 2 - 10 µg per 500 µl (1-3mg/ml) of cell lysate. WB 2 µg/ml |
| Positive control | K562 cell lysate |
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