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Fibroblast Growth Factor Receptor 1 (FGFR1) (M5G10) antibody
Fibroblast Growth Factor Receptor 1, FGFR-1
Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1
Fms-like tyrosine kinase 2, FLT-2
N-sam
Proto-oncogene c-Fgr
CD_antigen : CD331
CEK
FLG
HH2
OGD
KAL2
HBGFR
HRTFDS
Gene name : FGFR1
Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1
Fms-like tyrosine kinase 2, FLT-2
N-sam
Proto-oncogene c-Fgr
CD_antigen : CD331
CEK
FLG
HH2
OGD
KAL2
HBGFR
HRTFDS
Gene name : FGFR1
As low as
€757.00
In stock
Ref
00096687
Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.
| ID Covalab | mab60174 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | M5G10 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Recombinant human ectodomain of FGFr1β expressed in E. coli beginning with proline 23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences. |
| Activity cross reaction | Reacts with both α (denatured) and β isoforms of human FGFR1. Epitope is within the sequence his241 and val267 between Ig loops II and III. Epitope is masked in undenatured FGFr1α. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | None |
| Storage instructions | Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles. |
| Target | Fibroblast Growth Factor Receptor 1 |
| Uniprot ID | P11362 |
| Gene ID | 2260 |
| Applications | FC, ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC (1µg/1x10^6 cells) IHC (5 µg/ml ) WB (1 µg/ml) |
| Publication | * Xu J, et al. J Biol Chem. 1992 Sep 5,267(25):17792-803. |
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