Myelin Basic Protein (MBP) functions in the nervous system in myelination and is expressed in oligodendrocytes following differentiation.There are numerous isoforms generated by differential splicing events and post-translational modifications that have specialized functions.These functions include participation in signaling pathways prior to myelination, myelination or the re-myelination process following neural injury.
|Product type||Primary antibodies|
|Immunogen||Reacts with residues 49-62 of the 33 kDa human, mouse and rat MBP protein.|
|Activity cross reaction||Reacts with MBP from human, mouse and rat. Antibody detects primarily the 22 kDa isoform.|
|Species||Hu, Ms, Rat|
|Storage instructions||Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
|Target||Myelin Basic Protein|
|Applications||ELISA, ICC, IHC, WB|
|Working dilutions||Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC (1:100 - 1:200)
WB (1:500 - 1:1000)
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