ATG16L1 / ATG16L (C-Terminus) antibody

Autophagy-related protein 16-1, APG16-like 1, WD repeat domain 30
Gene name: ATG16L1, APG16L, APG16L beta, ATG16L, IBD10, ATG16A, WDR30
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Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
More Information
ID Covalab pab75590
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Goat
Immunogen Synthetic peptide C-KVEKVLSKQHSSSIN from an internal region (near the C-terminus) of human ATG16L1 (NP_110430.5; NP_060444.3). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Opossum (100%).
Activity cross reaction Reacts with the C-terminus part of human ATG16L1 / ATG16L. Cross reacts with mouse, monkey, rat ans hamster protein. This antibody is expected to recognize both reported isoforms (NP_110430.5 and NP_060444.3).
Species Hu, Ms, Rat
Labelling None
Form Antigen affinity purified
Preservative 0.02% NaN3
Storage instructions Store at -20°C. Minimize freezing and thawing.
Target ATG16L1 / ATG16L
Uniprot ID Q676U5
Gene ID 55054
Applications ELISA, IHC - P
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
ELISA 1:32000,
IHC-P 3.75 µg/ml
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