p53 antibody (B-F34)

Cellular tumor antigen p53
Antigen NY-CO-13
Phosphoprotein p53
Tumor suppressor p53
Gene name: TP53, P53
As low as €283.10
In stock
Ref
00036985
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
More Information
ID Covalab mab30071
Product type Primary antibodies
Clonality Monoclonal antibody
Clone B-F34
Isotype IgG2b / Kappa
Raised in Mouse
Immunogen Recombinant p53 protein
Activity cross reaction Reacts with wild type and mutant p53, the epitope is within residues 18-30 of human p53
Species Hu
Labelling None
Form Purified
Preservative None
Storage instructions Stable at +2-8°C for 12 months
For longer storage, freeze aliquots
Antibodies are guaranteed for 6 months from date of receipt.
Target p53
Uniprot ID P04637
Gene ID 7157
Applications ELISA
Working dilutions Optimal dilutions should be determined by the end user.
Write Your Own Review
Only registered users can write reviews. Please Sign in or create an account