p53 antibody (B-F34)

Cellular tumor antigen p53
Antigen NY-CO-13
Phosphoprotein p53
Tumor suppressor p53
Gene name: TP53, P53
As low as €283.10
In stock
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
More Information
ID Covalab mab30071
Product type Primary antibodies
Clonality Monoclonal antibody
Clone B-F34
Isotype IgG2b / Kappa
Raised in Mouse
Immunogen Recombinant p53 protein
Activity cross reaction Reacts with wild type and mutant p53, the epitope is within residues 18-30 of human p53
Species Hu
Labelling None
Form Purified
Preservative None
Storage instructions Stable at +2-8°C for 12 months
For longer storage, freeze aliquots
Antibodies are guaranteed for 6 months from date of receipt.
Target p53
Uniprot ID P04637
Gene ID 7157
Applications ELISA
Working dilutions Optimal dilutions should be determined by the end user.
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