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CD126 antibody (B-F19)
Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA
IL-6R 1
Membrane glycoprotein 80, gp80
CD126
Gene name: IL6R
IL-6R 1
Membrane glycoprotein 80, gp80
CD126
Gene name: IL6R
As low as
€283.10
In stock
Ref
00036923
CD126 is the alpha subunit of IL-6 receptor and needs to be associated to IL6ST to transduce signals.
| ID Covalab | mab30009 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | B-F19 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | CD126/gp80 transfected CHO cell line |
| Activity cross reaction | Reacts with human interleukin-6 Receptor α subunit, IL-6 Ra, IL-6 R, a 80 kDa protein. Recognizes both soluble and membrane bound IL-6 R |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | Azide free |
| Storage instructions | Stable at +2-8°C for 12 months For longer storage, freeze aliquots |
| Target | CD126 / IL-6R |
| Uniprot ID | P08887 |
| Gene ID | 3570 |
| Applications | ELISA, FA, FC, IHC |
| Working dilutions | Blocks IL-6 induced proliferation of XG-1 cell line Blocks IL-6 binding to its receptor IHC, WB : not tested |
| Publication | * Larregina AT et al. Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants. Immunology. 1997 Jun,91(2):303-13. * Mouthon MA et al. Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis. Blood. 1994 Aug 15,84(4):1085-97. |
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