CD126 antibody (B-F19)

Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA
IL-6R 1
Membrane glycoprotein 80, gp80
CD126
Gene name: IL6R
As low as €234.00
In stock
Ref
00036923
CD126 is the alpha subunit of IL-6 receptor and needs to be associated to IL6ST to transduce signals.
More Information
ID Covalab mab30009
Product type Primary antibodies
Clonality Monoclonal antibody
Clone B-F19
Isotype IgG1
Raised in Mouse
Immunogen CD126/gp80 transfected CHO cell line
Activity cross reaction Reacts with human interleukin-6 Receptor α subunit, IL-6 Ra, IL-6 R, a 80 kDa protein. Recognizes both soluble and membrane bound IL-6 R
Species Hu
Labelling None
Form Purified
Preservative Azide free
Storage instructions Stable at +2-8°C for 12 months
For longer storage, freeze aliquots
Target CD126 / IL-6R
Uniprot ID P08887
Gene ID 3570
Applications ELISA, FA, FC, IHC
Working dilutions Blocks IL-6 induced proliferation of XG-1 cell line
Blocks IL-6 binding to its receptor
IHC, WB : not tested
Publication * Larregina AT et al. Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants. Immunology. 1997 Jun,91(2):303-13.
* Mouthon MA et al. Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis. Blood. 1994 Aug 15,84(4):1085-97.
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