NOTCH4 antibody

Neurogenic locus notch homolog protein 4, Notch 4, hNotch4
Gene name: NOTCH4, INT3
Out of stock
Ref
00036333
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).
More Information
ID Covalab pab51030
Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Raised in Rabbit
Immunogen KLH conjugated synthetic peptide comprised of amino acids 1984 - 200 [CGPPALQEMPINQGGEGKK] of the human NOTCH homolog 4 (NOTCH4) protein.
Activity cross reaction Reacts with human NOTCH4.
Species Hu
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target NOTCH4
Uniprot ID Q99466
Applications ELISA, ICC, IF, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
WB (1:500 - 1:1000)
ELISA (1:100 - 1:2000)
ICC/IF (1:50 - 1:100)
IHC (1:50 - 1:200)
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