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NOTCH4 antibody
Neurogenic locus notch homolog protein 4, Notch 4, hNotch4
Gene name: NOTCH4, INT3
Gene name: NOTCH4, INT3
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00036333
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).
ID Covalab | pab51030 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Isotype | IgG |
Raised in | Rabbit |
Immunogen | KLH conjugated synthetic peptide comprised of amino acids 1984 - 200 [CGPPALQEMPINQGGEGKK] of the human NOTCH homolog 4 (NOTCH4) protein. |
Activity cross reaction | Reacts with human NOTCH4. |
Species | Hu |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.02% |
Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
Target | NOTCH4 |
Uniprot ID | Q99466 |
Applications | ELISA, ICC, IF, IHC, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB (1:500 - 1:1000) ELISA (1:100 - 1:2000) ICC/IF (1:50 - 1:100) IHC (1:50 - 1:200) |
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